Quote From: joyceymayMy sister has had bipolar disorder since she was a teenager, for over 30 years. For all of that time, her doctors have had an extremely hard time coming up with the right combination of medications to help her. (Lithium and other common meds have not helped her.) As a result, she is depressed most of the time. She is not suicidal, but it's hard to get her to do anything. She has other health issues that complicate things further. She has also had adverse reactions to medications. On several occasions, anti-depressants have made her manic and psychotic. Once she went into respiratory failure and was in intensive care for over a week. 
 
I am convinced that medications alone are not enough for her. I think she needs to modify her diet. (I think she has a number of food allergies, sensitivities, and addictions to certain foods that contribute to her symptoms. This is the case with other family members, including me.) I also strongly believe that she needs Cognitive Behavior Therapy. The problem is that she resists these alternatives. She has had bad experiences with "talk therapy" in the past and gets angry at me when I even bring up the subject of modifying her diet, even when I tell her it's not about losing weight but about feeling better. 
 
I just want to help my sister. I think she thinks that I'm judging her, that I think I'm better than her because I haven't suffered as much as she has. It's even harder for me to provide her with support because I live thousands of miles away from her. Is there anything that I can say or do to help her? Or should I just give up, and accept that the quality of her life will never get better? 
Some time ago on a show Dr. Phil did on ADD I think it was...the other doctor Frank Lawless I think his name is...I could check but I'm too lazy right now so if i got the name wrong i apologize...anyway he mentioned vitamin B6...he also said it takes at least 6 weeks to take effect....I remembered a doctor I saw years ago suggested B6 for my PMS and I didn't really take him seriously because i wasn't' aware of the power of nutrition...so anyway I still didn't try it right away...but a few months ago I started taking B6 and I took it everyday for 6 weeks...my last two periods have been virtually PMS free...the first time I was too afraid to believe it so I waited before getting my hopes up...when I recently started my second period since taking B6 and realized I had only been PMSing for 3 days I burst into tears. I have suffered with severe PMS since my teens...it usually lasted between 10 and 14 days out of every month with a list of symptoms as long as my arm...I still am afraid to get my hopes up and I am noticing now that when I take the B6 I feel a little restless...I am taking 100mg a day...I am going to try 50mg for awhile and see what that does. I also did some research and found this...maybe you could share it with your sister...
Vitamin B6...And Mental Health
A study found plasma pyridoxal-5-phosphate (active vitamin B6) levels were about 48% lower in depressed patients than in controls, a statistically significant finding. 57% of depressed patients, but none of the controls, were B6-deficient. When B6 nutriture was evaluated by enzyme stimulation testing (a more sensitive method), all the depressed patients and none of the controls were deficient. [Russ CS et al. Vitamin B6 status of depressed and obsessive-compulsive patients. Nutr Rep Int 27( 4): pp.867-73, 1983]
A deficiency of vitamin B6 (pyridoxine) causes extreme anxiety, nervousness, confusion, and melancholy. Vitamin B6 is easily destroyed by heavy use of alcohol, drugs and refined sugars.