I Think it all has to do with what you like in a person and age really doesn't matter. I myself am 23 and my boyfriend of a year is 42 and i will tell you we have so much fun together and never run out of things to say to each other. If he is mature enough for her then they should be together and be happy they will in time find if they can be together. Everyone once in there lifetime has wanted to date and older or younger person and it doesn't hurt to try it out if it works, it works if not they move on.
Chemical Imbalance has nothing to do with it if you fall in love with that person you are going to love them no matter what, if you are the same age or not.